Table 6. Physiological parameters and genotypic classes for lipoprotein lipase gene; -53 G<C promoter polymorphism in insulin resistant and non-insulin resistant subjects.
| Insulin resistant | Non-insulin resistant | ||||||
|---|---|---|---|---|---|---|---|
| GG (n = 190) |
GC (n = 37) |
CC (n = 8) |
GG (n = 397) |
GC (n = 3) |
CC (n = 7) |
GC+CC* (n = 3+7) |
|
| BMI | 29.7 ± 5.4 | 30.8 ± 4.5 | 35.4 ± 6.6 | 27.4 ± 2.0 | 28.0 ± 5.4 | 34.0 ± 6.8 | 32.0 ± 6.4 |
| p-value | 0.009 | 0.016 | 0.022 | ||||
| Fasting glucose, mg/dL | 119.3 ± 18.6 | 116.1 ± 16.8 | 119.8 ± 27.8 | 103.7 ± 13.7 | 120.2 ± 23.8 | 109.0 ± 7.5 | 112.4 ± 13.9 |
| p-value | 0.624 | 0.071 | 0.048 | ||||
| Fasting insulin, mU/mL | 19.4 ± 6.4 | 24.2 ± 9.9 | 27.0 ± 6.1 | 4.2 ± 1.6 | 7.7 ± 3.3 | 8.9 ± 2.7 | 7.1 ± 2.7 |
| p-value | < 0.001 | 0.005 | 0.013 | ||||
| HOMA index | 5.6 ± 2.0 | 6.8 ± 2.4 | 7.7 ± 2.1 | 1.4 ± 0.5 | 1.9 ± 0.8 | 2.8 ± 0.7 | 2.3 ± 0.7 |
| p-value | <0.001 | 0.006 | 0.027 | ||||
| Percentage body fat | 34.8 ± 7.1 | 34.2 ± 8.0 | 39.8 ± 6.7 | 30.8 ± 7.6 | 29.3 ± 8.7 | 36.6 ± 5.8 | 34.4 ± 7.2 |
| p-value | 0.137 | 0.125 | 0.135 | ||||
| FM, kg | 28.9 ± 9.5 | 27.7 ± 9.6 | 33.3 ± 10.8 | 23.3 ± 9.0 | 19.1 ± 8.3 | 29.4 ± 10.9 | 26.3 ± 10.9 |
| p-value | 0.315 | 0.148 | 0.296 | ||||
Data presented as mean±SD.
HOMA index: homeostasis model assessment index; FM: fat mass; BMI: body mass index.
*GG vs. GC+CC.