Table 5.
Multiple regression results: total PCL-R scores, Major Drug Use, as predictors of DRUG > FOOD-related hemodynamic activity among the dependent group.
| Region | Hemi. | MNI (x, y, z) | t | Cluster size |
|---|---|---|---|---|
| PCL-R | ||||
| Positive | ||||
| Insula | R | 36, –15, –15 | 3.46† | 151 |
| R | 36, –12, –21 | 3.34† | ||
| Amygdala | L | –30, –3, –24 | 2.95† | 23 |
| Negative | ||||
| No significant results | ||||
| Major Drug Use | ||||
| No significant results | ||||
| PCL-R ∗ Major Drug Use | ||||
| DMPFC | R | 24, 30, 33 | 5.28∗ | 150 |
| Superior frontal cortex | R | 15, 27, 48 | 3.61 | |
| Insula | R | 39, –9, –9 | 2.78† | 63 |
| DMPFC | L | –15, 42, 36 | 3.40† | 168 |
| L | 3, 48, 30 | 2.72† | ||
| Caudate | L | –3, –3, 12 | 3.72† | 33 |
| L | –6, 0, 15 | 3.63† | ||
All regions show significant activity at p(uncorr) < 0.001; ∗p(FWE) < 0.05; †p(svc-FWE) < 0.05; DMPFC = Dorsomedial prefrontal cortex.