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. 2018 Sep 4;8:292. doi: 10.3389/fcimb.2018.00292

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Copyright © 2018 Ravichandran, Zhong, Wang, Yu, Zhang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparative analysis of CviR with LasR using RCSB PDB Protein Comparison Tool. (A) Molecular comparison of CviR vs LasR. (A) The alignment of the active site residues (Tyr, Trp, Asp, Ser) which are crucial for the interactions. (B) The molecular interaction of (N-hexanoyl-L-Homoserine lactone (C₆HSL) against CviR (C) The molecular interaction of N-(3-Oxododecanoyl)-L-homoserine lactone (3-Oxo-C₁₂-HSL) with LasR.