Table V.
Predictors of adverse limb outcomes from multivariable Cox regression models
| Hazard ratio | 95% CI | |
|---|---|---|
|
Demographics |
||
| Age, years | ||
| 65–74 | 0.66 | 0.62–0.70 |
| 75–84 | 0.43 | 0.40–0.46 |
| 85+ | 0.32 | 0.29–0.37 |
| Race | ||
| White | Reference | |
| Black | 1.35 | 1.27–1.44 |
| Other | 1.01 | 0.92–1.12 |
| Unknown | 0.80 | 0.73–0.87 |
| Comorbidities | ||
| Atherosclerosis | 0.76 | 0.65–0.89 |
| Myocardial infarction | 1.40 | 1.17–1.68 |
| CHF | 1.26 | 1.17–1.35 |
| Valve disease | 0.95 | 0.84–1.07 |
| Arrhythmia | 1.07 | 1.00–1.15 |
| Cerebrovascular disease | 1.14 | 1.06–1.22 |
| Hypertension | 1.06 | 0.99–1.13 |
| COPD | 0.88 | 0.82–0.93 |
| DM | 1.93 | 1.83–2.03 |
| Renal disease | 1.51 | 1.41–1.61 |
| Dialysis | 1.83 | 1.53–2.19 |
| Liver disease | 1.04 | 0.93–1.17 |
| Cancer | 0.97 | 0.89–1.05 |
| Psychiatric illness | 0.93 | 0.83–1.05 |
| Diagnosis of PAD | ||
| Stable PAD | Reference | |
| CLI diagnosis or amputation | 6.28 | 5.82–6.76 |
| Revascularization in absence of CLI or amputation |
1.30 | 1.10–1.53 |
| Statins | ||
| None | Reference | |
| Statin, low-moderate intensity | 1.26 | 1.19–1.34 |
| Statin, high intensity | 1.02 | 0.96–1.08 |
CHF, Congestive heart failure; CI, confidence interval; CLI, critical limb ischemia; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; PAD, peripheral artery disease.