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. 2018 Sep 4;9:2088. doi: 10.3389/fmicb.2018.02088

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Copyright © 2018 Jaguva Vasudevan, Kreimer, Schulz, Krikoni, Schumann, Häussinger, Münk and Goering.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Phenotypical consequences of L1 siRNA treatment in selected UCCs. (A) Cell viability and (B) caspase activity (both depicted as percent of control) were determined in VM-CUB1 and 5637 UCCs after 72 h treatment with 20 nM control siRNA or L1 siRNAs (each n = 5–8). Cell cycle distribution in (C) VM-CUB1 and (D) 5637 cells (each n = 2). Data were represented as means ± standard deviations (error bars). P-values for (A,B) were calculated using Mann–Whitney U Test. Asterisk represents statistically significant difference: ^∗P < 0.05 and ns, not significant.