Table 3.
Comparison of Ancillary Testing Between Subgroupsa
Ancillary test | IH (N=100) | CRb (N=100) | PRb (N=100) |
P value |
|||
---|---|---|---|---|---|---|---|
Overall | IH vs CR | IH vs PR | CR vs PR | ||||
No. of IHC stains, mean | 1.5 | 2.8 | 4.8 | <.001 | .003 | <.001 | .008 |
With ancillary testing (%) | |||||||
Flow cytometry | 73 | 83 | 90 | .007 | .09 | .002 | .15 |
IHC | 48 | 69 | 63 | .008 | .003 | .03 | .37 |
Cytogenetics/karyotype | 37 | 72 | 54 | <.001 | <.001 | .02 | .008 |
FISH | 23 | 44 | 31 | .006 | .002 | .20 | .06 |
NGS | 2 | 2 | 3 | .86 | >.99 | .65 | .65 |
Other molecular | 15 | 19 | 17 | .75 | .45 | .70 | .71 |
CR = clinically referred; IH = in-house; IHC = immunohistochemistry; FISH = fluorescence in situ hybridization; NGS = next-generation sequencing; PR = pathologist referred.
The CR and PR ancillary studies by both outside and Mayo Clinic pathologists included.