Table 3.

Adjusted Multivariable Analysis of Risk Factors for Survival^a,b

Variable	All-cause mortality (n=80)
	Multivariable HR (95% CIs)c	P
Peripheral adenopathies	0.76 (0.45-1.28)	.30
Platelets <100,000 cells per mm3	1.92 (0.72-5.15)	.20
WBC <4000 cells per mm3	1.54 (0.83-2.85)	.17
Natremia <130 mmol/L	1.41 (0.84-2.39)	.20
Disseminated intravascular coagulation	1.56 (0.81-3.00)	.19
Number of infectious triggers
0
1	0.95 (0.56-1.61)	.85
≥2	3.14 (1.28-7.68)	.01
Microbiological classification	NCd
No infection
Bacteria
Virus
Fungi/parasites
Mixed
Therapeutic interventions
No immunosuppressive drugs	Reference
Glucocorticoid monotherapy	1.37 (0.65-2.92)	.41
ID/IVIG/biological therapies	0.78 (0.33-1.85)	.57
Chemotherapy	0.71 (0.32-1.54)	.38

^aID = immunosuppressive drug; IVIG = intravenous immunoglobulin; NC = not calculated; HR = hazard ratio; WBC = white blood cell.

^bValues are represented as HRs and 95% CIs.

^cMultivariable Cox proportional hazards regression analysis adjusted for age at diagnosis, sex, and underlying disease group.

^dTo avoid multicollinearity with the number of triggers, the trigger group was not included in the model.