Fig. 3.

A. Old cortical microhemorrhage, probably related to amyloid angiopathy, in an elderly patient. The neuropil appears cystic, there is slight indentation of the pial surface (secondary to underlying tissue loss) and hemosiderin-laden macrophages are seen in abundance. Arrows indicate extension of the microhemorrhage into the subarachnoid space. B. Magnified view from edge of the brain microbleed (BMB). Arrow indicates a gemistocyte that has either phagocytosed altered blood pigment, or shows it encrusted on the cell membrane. (Images are from H&E-stained sections).