Table 3.
Percentage of subjects who reported various EoE symptoms within 12 months prior to enrollment and who reported various endoscopic findings at diagnosis, categorized by age at enrollment, and compared with respect to race.
| Total (n=705) |
Patients <11 years of age |
Patients 11–17 years of age |
Patients ≥18 years of age |
Age comparison |
% among whites (n=620) |
% among non- whites (n=85) |
Race comparison |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N Total# |
% Cases |
N Total# |
% Cases |
N Total# |
% Cases |
N Total# |
% Cases |
P-Value** | N Total# |
% Cases |
N Total# |
% Cases |
P-value | |
| Symptoms | ||||||||||||||
| Abdominal Pain | 704 | 53.6 | 344 | 57.6 | 189 | 57.1 | 171 | 41.5 | 0.001 | 619 | 53.8 | 85 | 51.8 | 0.73 |
| Nausea | 703 | 40 | 343 | 38.8 | 189 | 44.4 | 171 | 37.4 | 0.34 | 618 | 40.3 | 85 | 37.6 | 0.72 |
| Emesis | 705 | 40 | 345 | 47 | 189 | 40.2 | 171 | 25.7 | < 0.0001 | 620 | 38.4 | 85 | 51.8 | 0.02 |
| Heartburn | 696 | 37.2 | 336 | 22.9 | 189 | 42.9 | 171 | 59.1 | < 0.0001 | 612 | 39.5 | 84 | 20.2 | 0.0005 |
| Chest Pain | 703 | 21.1 | 343 | 15.7 | 189 | 25.9 | 171 | 26.3 | 0.003 | 618 | 21.2 | 85 | 20.0 | 0.89 |
| Gastroesophageal Reflux | 705 | 51.3 | 345 | 43.5 | 189 | 52.4 | 171 | 66.1 | < 0.0001 | 620 | 52.9 | 85 | 40.0 | 0.03 |
| Dysphagia | 705 | 50.5 | 345 | 38.3 | 189 | 52.4 | 171 | 73.1 | < 0.0001 | 620 | 52.4 | 85 | 36.5 | 0.008 |
| Esophageal Food Impactions | 704 | 38.1 | 344 | 20.3 | 189 | 42.3 | 171 | 69 | < 0.0001 | 619 | 40.5 | 85 | 20.0 | 0.0002 |
| Diarrhea | 705 | 32.1 | 345 | 32.2 | 189 | 27.5 | 171 | 36.8 | 0.17 | 620 | 33.1 | 85 | 24.7 | 0.14 |
| Bloody Stools | 705 | 7.5 | 345 | 7.5 | 189 | 6.9 | 171 | 8.2 | 0.90 | 620 | 7.3 | 85 | 9.4 | 0.51 |
| Food impactions requiring urgent endoscopic removal | 705 | 6.1 | 345 | 0.9 | 189 | 5.8 | 171 | 17.0 | <0.0001 | |||||
| Esophageal dilation | 700 | 9.9 | 342 | 0.9 | 187 | 5.3 | 171 | 32.7 | <0.0001 | |||||
| Endoscopic Findings at diagnosis* | ||||||||||||||
| Furrows | 487 | 68.4 | 219 | 63.5 | 127 | 74 | 141 | 70.9 | 0.10 | 439 | 69.7 | 48 | 56.3 | 0.07 |
| White Plaques | 478 | 55 | 218 | 53.7 | 127 | 58.3 | 133 | 54.1 | 0.69 | 433 | 54.7 | 45 | 57.8 | 0.75 |
| Loss of Vascular Pattern | 334 | 32.6 | 148 | 27.7 | 85 | 40 | 101 | 33.7 | 0.15 | 306 | 32.7 | 28 | 32.1 | 1.00 |
| Rings | 437 | 16.5 | 193 | 3.1 | 108 | 11.1 | 136 | 39.7 | < 0.0001 | 398 | 17.8 | 39 | 2.6 | 0.01 |
| Stricture | 434 | 10.1 | 192 | 1.6 | 114 | 6.1 | 128 | 26.6 | < 0.0001 | 394 | 10.7 | 40 | 5.0 | 0.41 |
| Shearing | 378 | 8.5 | 174 | 9.8 | 100 | 10 | 104 | 4.8 | 0.27 | 342 | 8.2 | 36 | 11.1 | 0.53 |
#
Number of subjects with data available.
*
Since full endoscopy reports were not a required document for enrollment, and since variability in reporting of endoscopic features was present among endoscopists, some features were not reported on some subjects. In addition, p-values for endoscopic findings were calculated excluding missing values and N/A values in the questionnaires.
**
P-value is the result of comparison of all 3 age groups.