Table 2.

Extension of the Concept C0004057 Named “Aspirin” in the UMLS

Semantic types:

Organic Chemical Pharmacologic Substance Biologically Active Substance

Definitions:

Aspirin: Acetylsalicylic acid, a drug having anti-inflammatory, analgesic, and antipyretic effects; it is the prototype of the nonsteroidal anti-inflammatory agents whose mechanism of action is inhibition of prostaglandin synthesis; used for relief of pain and fever, for treatment of rheumatoid arthritis and osteoarthritis, and for antiplatelet therapy to reduce the risk of recurrent transient ischemic attacks or of cerebrovascular accident. (From Dorland's Dictionary, 27th ed.) Ecotrin: Trademark for a preparation of aspirin. Dorland's Illustrated Medical Dictionary 27th edition. (From Dorland's Dictionary, 27th ed.) Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It also has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase, which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopœia, 30th ed.)

Phrases: See ▶

Note: The UMLS relationships that are linked to concept C0004057 have been omitted from the table to simplify the presentation, but they are crucial to an understanding of the concept. Some of the relevant relationships are shown in Figures ▶ and ▶. Notice that the three definitions linked to C0004057 differ, even to the point that Dorland's Dictionary, from which two definitions were acquired, provides two separate entries.