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. 2018 Aug 13;22(5):621–629. doi: 10.1007/s40291-018-0355-7
The analysis of IL-13/STAT6/SOCS3 expression could be useful as a support tool in non-small cell lung carcinoma (NSCLC) histopathological examination.
The presence of a negative correlation between STAT6 and SOCS3 confirms that suppressors of cytokine signaling (SOCS) act as a negative regulator of signal transducer and activator of transcription (STAT).
An accurate subclassification based on molecular analysis could, in the future, offer more personalized therapies for NSCLC patients.