Table 3.
Mean reductions in VAS scores for individual dyspeptic symptoms in the per-protocol population
| Variable | Nimesulide/pantoprazole (mean ± SD) | Naproxen/esomeprazole (mean ± SD) | Mean difference | 95% CI | P-value |
|---|---|---|---|---|---|
| Baseline vs Day 7 | |||||
| Nausea | 20.41±3.06 | 16.55±3.16 | 3.77 | −1.60 to 9.15 | 0.17 |
| Abdominal discomfort/pain | 28.71±3.02 | 29.76±2.92 | 1.05 | −3.97 to 6.06 | 0.68 |
| Epigastric burning | 37.21±3.14 | 38.83±3.03 | 1.63 | −3.59 to 6.84 | 0.54 |
| Postprandial fullness | 26.33±2.81 | 28.34±2.73 | 1.79 | −2.98 to 6.56 | 0.46 |
| Baseline vs Day 14 | |||||
| Nausea | 20.26±3.14 | 22.41±3.03 | 2.26 | −3.17 to 7.69 | 0.41 |
| Abdominal discomfort/pain | 32.28±2.92 | 34.20±2.81 | 1.93 | −2.98 to 6.83 | 0.44 |
| Epigastric burning | 41.01±3.14 | 40.07±3.02 | 0.52 | −5.55 to 4.52 | 0.84 |
| Postprandial fullness | 30.25±2.81 | 31.93±2.72 | 0.89 | −3.96 to 5.73 | 0.72 |
Abbreviations: CI, confidence interval; SD, standard deviation; VAS, visual analog scale.