Table 2.
Measures of diagnostic accuracy of US examination, FNAC and core needle biopsy
| Results, n (%) | |||
|---|---|---|---|
| FNAC (n = 58) | US examination (n = 58)a | CNB (n = 10) | |
| True positive | 0 | 2 (3) | 0 |
| Tumour | |||
| Breast cancer | n/a | 1 (50) | n/a |
| Melanoma | n/a | 1 (50) | n/a |
| SN location | |||
| Axilla | n/a | 1 (50) | n/a |
| Groin | n/a | 1 (50) | n/a |
| False positive | 1 (2) | 6 (10) | 0 |
| Tumour | |||
| Breast cancer | 0 | 2 (33) | n/a |
| Melanoma | 1 (100) | 4 (66) | n/a |
| SN location | |||
| Axilla | 1 (100) | 6 (100) | n/a |
| Groin | 0 | 0 | n/a |
| True negative | 43 (74) | 38 (66) | 9 (90) |
| Tumour | |||
| Breast cancer | 17 (40) | 15 (40) | 9 (100) |
| Melanoma | 26 (61) | 23 (61) | 0 |
| SN location | |||
| Axilla | 36 (80)b | 29 (76) | 9 (100) |
| Groin | 9 (20) | 9 (24) | 0 |
| False negative | 14 (24) | 12 (21) | 1 (10) |
| Tumour | |||
| Breast cancer | 4 (29) | 3 (25) | 1 (100) |
| Melanoma | 10 (71) | 9 (75) | 0 |
| SN location | |||
| Axilla | 6 (43) | 5 (42) | 1 (100) |
| Groin | 8 (57) | 7 (58) | 0 |
| Measures, % (95% CI) | |||
| Sensitivity | 0 | 14 (3–38) | 0 |
| Specificity | 98 (90–100) | 86 (74–94) | 100 |
| Positive predictive value | 0 | 25 (5 – 59) | 0 |
| Negative predictive value | 75 (63–85) | 76 (63–86) | 90 (63–99) |
CI confidence interval, CNB core needle biopsy, FNAC fine needle aspiration cytology, n/a not applicable, US ultrasound
aAccording to the Berlin criteria, a malignant/suspicious sentinel node on US examination was recorded as positive
bTwo patients had SNs identified in the groin and axilla