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. 2018 Apr 26;45(11):1926–1933. doi: 10.1007/s00259-018-4014-3

Table 2.

Measures of diagnostic accuracy of US examination, FNAC and core needle biopsy

Results, n (%)
FNAC (n = 58) US examination (n = 58)a CNB (n = 10)
True positive 0 2 (3) 0
 Tumour
  Breast cancer n/a 1 (50) n/a
  Melanoma n/a 1 (50) n/a
 SN location
  Axilla n/a 1 (50) n/a
  Groin n/a 1 (50) n/a
False positive 1 (2) 6 (10) 0
 Tumour
  Breast cancer 0 2 (33) n/a
  Melanoma 1 (100) 4 (66) n/a
 SN location
  Axilla 1 (100) 6 (100) n/a
  Groin 0 0 n/a
True negative 43 (74) 38 (66) 9 (90)
 Tumour
  Breast cancer 17 (40) 15 (40) 9 (100)
  Melanoma 26 (61) 23 (61) 0
 SN location
  Axilla 36 (80)b 29 (76) 9 (100)
  Groin 9 (20) 9 (24) 0
False negative 14 (24) 12 (21) 1 (10)
 Tumour
  Breast cancer 4 (29) 3 (25) 1 (100)
  Melanoma 10 (71) 9 (75) 0
 SN location
  Axilla 6 (43) 5 (42) 1 (100)
  Groin 8 (57) 7 (58) 0
Measures, % (95% CI)
 Sensitivity 0 14 (3–38) 0
 Specificity 98 (90–100) 86 (74–94) 100
 Positive predictive value 0 25 (5 – 59) 0
 Negative predictive value 75 (63–85) 76 (63–86) 90 (63–99)

CI confidence interval, CNB core needle biopsy, FNAC fine needle aspiration cytology, n/a not applicable, US ultrasound

aAccording to the Berlin criteria, a malignant/suspicious sentinel node on US examination was recorded as positive

bTwo patients had SNs identified in the groin and axilla