Fig. 3.
Prediction of methyl group PCS. The PCS for the Leu/Val methyl groups of ntd-HSP90 were predicted using the published amide based Δχ tensor parameters (Lescanne et al. 2017) and the structure with PDB entry 3t0h (Li et al. 2012) and plotted against the experimental PCS. No fitting was performed. a For mutant 50C/54C the Q factor (Eq. 1) is 0.14 (Qa = 0.07, Eq. 2) b For mutant 101C/105C Q = 0.05 (Qa=0.025). c For mutant 149C/187C Q = 0.24 (Qa=0.12). The red line represents a perfect correlation