Table 1.
Behavioral domain | Test | Behavior of Bsn cKO mice as compared to WT |
---|---|---|
Activity and anxiety | Home cage activity | Hyperactive (Fig. 3a) |
Open field | No difference (Fig. 3b, and Online Resource 2a) | |
Light–dark test | No difference (Fig. 3c) | |
Novelty recognition and spatial learning | Novel object location | Non-significant trend towards novelty preference (Fig. 4e–h) |
Spatial discrimination/pattern separation | Increased preference for the novel location (Fig. 4a–d) | |
Morris water maze | No difference (Online Resource 4) | |
Fear learning | Contextual fear memory | Enhanced (Fig. 3d and Online Resource 2c) |
Cue fear memory | No difference (Fig. 3e and Online Resource 2d) | |
Active avoidance | No difference (Online Resource 2e) |