Table 3.
Association of single screen and conditional rescreen, and population (all, young, and old) with the presence and absence of HFHL25 and HFHL35, expressed as sensitivity, specificity, predictive values and likelihood ratios
| Screen | Degree HFHL | Population | Sensitivity | Specificity | PV+ | PV− | LR+ | LR− |
|---|---|---|---|---|---|---|---|---|
| Single screen | HFHL25 | All | 65% (22/34) | 63% (29/46) | 56% (22/39) | 71% (12/41) | 1.8 | 0.6 |
| ≤ 45 years | 50% (4/8) | 70% (23/33) | 29% (4/14) | 85% (23/27) | 1.7 | 0.7 | ||
| > 45 years | 69% (18/26) | 46% (6/13) | 72% (18/25) | 43% (6/14) | 1.3 | 0.7 | ||
| HFHL35 | All | 100% (18/18) | 66% (41/62) | 46% (18/39) | 100% (41/41) | 2.9 | – | |
| ≤ 45 years | 100% (3/3) | 71% (27/38) | 21% (3/14) | 100% (27/27) | 3.4 | – | ||
| > 45 years | 100% (15/15) | 58% (14/24) | 60% (15/25) | 100% (14/14) | 2.4 | – | ||
| Conditional rescreen | HFHL25 | All | 59% (20/34) | 93% (43/36) | 87% (20/23) | 75% (43/57) | 8.4 | 0.4 |
| ≤ 45 years | 38% (3/8) | 94% (31/33) | 60% (3/5) | 86% (31/36) | 6.3 | 0.7 | ||
| > 45 years | 65% (17/26) | 92% (12/13) | 94% (17/18) | 57% (12/21) | 8.1 | 0.4 | ||
| HFHL35 | All | 94% (17/18) | 90% (56/62) | 74% (17/23) | 98% (56/57) | 9.4 | 0.07 | |
| ≤ 45 years | 100% (3/3) | 95% (36/38) | 60% (3/5) | 100% (36/36) | 20 | – | ||
| > 45 years | 93% (14/15) | 83% (20/24) | 78% (14/18) | 95% (20/21) | 5.5 | 0.08 |
HFHL25 = high-frequency hearing loss for at least one ear, defined as a pure-tone average of the frequencies 3, 4, 6 kHz (PTA346) of 25 dB HL or worse. HFHL35 = high-frequency hearing loss for at least one ear, defined as a pure-tone average of the frequencies 3, 4, 6 kHz (PTA346) of 35 dB HL or worse
PV+ positive predictive value, PV− negative predictive value, LR+ positive likelihood ratio, LR− negative likelihood ratio