Table 4.
Region | Gene | Effect (contrasts nested) | Direction of change | Ratio | Nominal p val. | Corrected p val.a |
---|---|---|---|---|---|---|
Caudoputamen | Pdyn | Overall | 0.03 | 0.14 | ||
within males (GG vs AA) | ↓ | 0.68 | 0.002 | |||
Cnr1 | Overall | 0.009 | 0.56 | |||
within males (GG vs AA) | ↓ | 0.72 | 0.008 | |||
within AA (F vs M) | ↓ | 0.75 | 0.01 | |||
Nr3c2 | Overall | 0.03 | 0.54 | |||
within males (GG vs AA) | ↓ | 0.83 | 0.06 | |||
N. accumbens | Cnr2 | Overall | 0.02 | 0.54 | ||
within males (GG vs AA) | ↓ | 0.35 | 0.004 | |||
Hypothalamus | Oprk1 | Overall | 0.006 | 0.14 | ||
within females (GG vs AA) | ↓ | 0.68 | 0.00 | |||
within AA (F vs M) | ↑ | 1.27 | 0.03 | |||
Pdyn | Overall | 0.01 | 0.14 | |||
within females (GG vs AA) | ↓ | 0.65 | 0.002 | |||
within AA (F vs M) | ↑ | 1.46 | 0.005 | |||
Hippocampus | – | – | – | – | – | – |
Amygdala | Gal | Overall | 0.01 | 0.43 | ||
within males (GG vs AA) | ↑ | 3.19 | 0.01 | |||
within AA (F vs M) | ↑ | 2.58 | 0.04 |
aFalse discovery rate (5%)