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. 2018 Jul 9;92(9):2897–2911. doi: 10.1007/s00204-018-2257-1

Fig. 1.

Fig. 1

Compound structures. Chemical structures of the active compound 3i-1000 and its derivatives analysed herein. These molecules can formally be characterized by northern and southern parts that are connected via a linker unit as defined in the figure. The northern part is typically comprised of a para-phenylenediamine, whereas the southern part is typically comprised of an ortho-aryl-substituted heterocycle. The linker unit is a two-atom spacer consisting of a nitrogen atom and sp2 or sp3 carbon atom