Table 1.
Mean values ± SEM of additional measures activity for both schedule types, as well as the number of rats in each condition that completed the 45-min session without emitting a response for 180 s. Additional motoric measures are of the reward collection latencies, rate of magazine entries (magazine entries per second), and the rate of nontarget (blank) screen responses (nontarget responses/sec) for all experimental conditions. Italic type signifies significant effects
Reward collection latency | Magazine entries/sec | Nontarget responses/sec | No. of 45-min terminations | |||||
---|---|---|---|---|---|---|---|---|
PR4 | PREXP | PR4 | PREXP | PR4 | PREXP | PR4 | PREXP | |
Baseline | 1.20 ± 0.04* | 1.58 ± 0.11* | 0.08 ± 0.01 | 0.07 ± 0.01 | 0.03 ± 0.00 | 0.04 ± 0.01 | 33 | 14 |
Reward magnitude | ||||||||
1 pell | 1.11 ± 0.06 | 1.36 ± 0.09# | 0.07 ± 0.01# | 0.05 ± 0.00# | 0.02 ± 0.00 | 0.03 ± 0.01 | 5 | 2 |
3 pellets | 0.97 ± 0.08 | 0.94 ± 0.12# | 0.10 ± 0.01# | 0.08 ± 0.01 # | 0.02 ± 0.00 | 0.03 ± 0.01 | 8 | 6 |
Prefeeding | ||||||||
No feed | 1.39 ± 0.09 | 1.51 ± 0.13 | 0.06 ± 0.01* | 0.05 ± 0.00* | 0.02 ± 0.00 | 0.02 ± 0.00 | 3 | 2 |
Prefeed | 1.27 ± 0.05 | 1.56 ± 0.10 | 0.06 ± 0.01 | 0.04 ± 0.00 | 0.02 ± 0.00 | 0.03 ± 0.01 | 1 | 0 |
Raclopride | ||||||||
Vehicle | 1.23 ± 0.09* | 1.63 ± 0.15* | 0.08 ± 0.01* | 0.06 ± 0.01* | 0.02 ± 0.00 | 0.03 ± 0.01 | 0 | 0 |
0.03 mg/kg | 1.28 ± 0.06 | 1.58 ± 0.14 | 0.07 ± 0.01 | 0.05 ± 0.01 | 0.03 ± 0.01 | 0.04 ± 0.02 | 2 | 2 |
0.3 mg/kg | 1.44 ± 0.19* | 2.65 ± 0.72* | 0.05 ± 0.01 † | 0.04 ± 0.00 | 0.01 ± 0.00 † | 0.02 ± 0.01 | 1 | 0 |
Amphetamine | ||||||||
Vehicle | 1.44 ± 0.09* | 1.80 ± 0.12* | 0.09 ± 0.01 | 0.06 ± 0.01 | 0.04 ± 0.01 | 0.03 ± 0.01 | 1 | 0 |
0.1 mg/kg | 1.40 ± 0.08* | 1.71 ± 0.16* | 0.08 ± 0.01 | 0.06 ± 0.01 | 0.03 ± 0.01 | 0.03 ± 0.01 | 1 | 2 |
1 mg/kg | 1.35 ± 0.06 | 1.56 ± 0.09 | 0.10 ± 0.01 | 0.09 ± 0.01 † | 0.05 ± 0.01 | 0.05 ± 0.01 | 6 | 8 |
*A significant group difference between schedule types, p < .05. #A significant effect of increasing the reward magnitude, p < .05. †A significant effect relative to the vehicle condition p < .05