Table 1.

Platelet count responses to first-line treatment with high-dose dexamethasone in selected randomized controlled trials in adults with newly diagnosed immune thrombocytopenia (ITP)

Trial	Regimen	n	Median time to response		CRR at 3 months		ORR at 6 months
Wei et al. [11]	Dexamethasone 40 mg/day d1–4 × 1–2 cycles	95	3 months	p < 0.01	48%	p < 0.01	40%	p > 0.05
	Prednisone 1 mg/kg/day × 4 weeks	97	6 months		26%		41%
Bae et al. [12]	Dexamethasone 40 mg/day d1–4 × 1 cycle	76	–		–		25%	p > 0.05
	Prednisone 1 mg/kg/day × 4 weeks	75	–		–		36%

d day, CRR complete response rate defined as platelet count ≥100,000/µL, ORR overall response rate defined as platelet count ≥30,000/µL