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. 2018 Apr 26;25(5):605–613. doi: 10.1007/s12282-018-0861-9

Table 5.

Rates of primary resistance to T-DM1 per HER2 gene amplification in ctDNA and hormone receptor status

HER2 gene amplification in ctDNA
Positive (N/total) Negative (N/total)
Hormone receptor status ER and PR negative (N/total) 0/4 0/5
ER and/or PR positive (N/total) 0/1 4/6

N number of patients with primary resistance to T-DM1