Table 3.
Adverse event | Incidence, n (%) | |||
---|---|---|---|---|
Grade 1 | Grade 2 | Grade 3 | Grade 4 | |
Neutropenia | 8 (27.6) | 8 (27.6) | 4 (13.8) | 4 (13.8) |
Febrile neutropenia | 1 (13.8) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Anemia | 9 (31.03%) | 1 (3.5%) | 0 (0.0) | 0 (0.0) |
Thrombocytopenia | 4 (13.8%) | 3 (10.3%) | 0 (0.0) | 0 (0.0) |
ALT elevation | 1 (3.5%) | 2 (6.9%) | 0 (0.0) | 0 (0.0) |
TBIL elevation | 2 (6.9%) | 1 (3.5%) | 0 (0.0) | 0 (0.0) |
Hair loss | 9 (31.03%) | 2 (6.9%) | 0 (0.0) | 0 (0.0) |
Fatigue | 3 (10.3%) | 3 (10.3%) | 0 (0.0) | 0 (0.0) |
Hand–foot syndrome | 0 (0.0) | 3 (10.3%) | 1 (3.5%) | 0 (0.0) |
Peripheral neuropathy | 4 (13.8%) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Anorexia | 16 (55.2%) | 4 (13.8%) | 0 (0.0) | 0 (0.0) |
Nausea | 14 (48.3%) | 6 (20.7%) | 0 (0.0) | 0 (0.0) |
Vomiting | 5 (17.2%) | 2 (6.9%) | 0 (0.0) | 0 (0.0) |
Stomatitis | 0 (0.0) | 2 (6.9%) | 0 (0.0) | 0 (0.0) |
Diarrhea | 2 (6.9%) | 1 (3.5%) | 2 (6.9%) | 0 (0.0) |
Rash | 2 (6.9%) | 0 (0.0) | 1 (3.5%) | 0 (0.0) |