Table 2.
Incidence of nausea, vomiting, oral mucositis, and liver toxicity, N (%)
| PHT (n = 70) | LEV (n = 34) | p value | |
|---|---|---|---|
| Nausea | |||
| All grades | 50 (71.4) | 30 (88.2) | 0.08 |
| Grade 3 ≤ | 12 (17.1) | 1 (2.9) | 0.06 |
| Vomiting | |||
| All grades | 34 (48.6) | 18 (52.9) | 0.84 |
| Grade 3 ≤ | 3 (4.3) | 0 | 0.55 |
| Mucositis oral | |||
| Until transplant day | |||
| All grades | 41 (58.6) | 13 (38.2) | 0.06 |
| Grade 3 ≤ | 0 | 0 | |
| Until day 28 | |||
| All grades | 65 (92.9) | 32 (94.1) | 1 |
| Grade 3 ≤ | 25 (35.7) | 12 (35.3) | 1 |
| T-Bil | |||
| All grades | 29 (41.4) | 10 (29.4) | 0.28 |
| Grade 3 ≤ | 2 (2.9) | 0 | 1 |
| VOD/SOS | 2 (2.9) | 0 | 1 |
PHT phenytoin, LEV levetiracetam, T-Bil total bilirubin, VOD/SOS veno-occlusive disease/sinusoidal obstruction syndrome