Fig. 4.

Overall and recurrence-free survival after perioperative period (91 days–5 years). HR hazard ratio, CI two-sided 95% confidence interval. A Kaplan–Meier analysis over all patients: 5-year overall survival rate open versus laparoscopic: 73.4 versus 82.1%, p = 0.001. B 5-year overall survival: Multivariate Cox regression analysis over all patients, adjustment for gender, age, previous carcinomas, synchronous carcinomas, grading, T-stage, N-stage, harvested lymph nodes, hospital classification, resection group, and postoperative therapy; reference: open approach. C Kaplan–Meier analysis over all patients: 5-year recurrence-free survival rate open vs. laparoscopic: 70.3 versus 75.9%, p = 0.061. D 5-year recurrence-free survival: Multivariate Cox regression analysis over all stages, adjustment for gender, age, previous carcinomas, synchronous carcinomas, grading, T-stage, N-stage, harvested lymph nodes, hospital classification, resection group, and postoperative therapy; reference: open approach