Table 6.

One linear hierarchical regression was performed for each group (controls, PD ON and PD OFF medication)

Group	Step	Independent variables	Unstandardized B	Std. error of B	Standardized B	p value
HC	Step 1	Average motion	− 0.055	18.62	− 0.001	ns
	Step 2	Average motion	0.203	17.50	0.002	ns
		BC of pain network	− 10.17	4.89	− 0.39	0.049
	Step 3	Average motion	− 8.65	16.88	− 0.09	ns
		BC of pain network	− 9.99	4.57	− 0.38	0.039
		GE of pain network	− 0.218	0.10	− 0.38	0.046
PD OFF	Step 1	Average motion	− 5.43	65.11	− 0.02	ns
	Step 2	Average motion	− 38.30	57.43	− 0.13	ns
		GE of pain network	0.171	0.059	0.55	0.009
PD ON	Step 1	Average motion	27.32	36.34	0.158	ns

To control for motion, average motion during scanning was entered at Step 1 as a covariate, after which a forward stepwise method was used to add significant independent variables to the model

BC betweenness centrality, GE global efficiency, ns not significant