Table 2.
Demographic and clinical characteristics for each cohort
| Strict NTMD general cohort n (%) | Expanded NTMD general cohort n (%) | Strict NTMD CRD cohort n (%) | Expanded NTMD CRD cohort n (%) | |
|---|---|---|---|---|
| Number of patients | n = 1262 | n = 10,543 | n = 482 | n = 4145 |
| Female | 601 (47.6) | 5774 (54.8) | 223 (46.3) | 2132 (51.4) |
| Age at NTMD, years (mean, SD) | 55.1 ± 18.5 | 56.0 ± 18.6 | 63.5 ± 14.8 | 62.6 ± 15.8 |
| Males | 55.5 ± 17.4 | 57.9 ± 18.0 | 62.9 ± 14.3 | 63.9 ± 15.5 |
| Females | 54.7 ± 19.6 | 54.4 ± 18.9 | 64.2 ± 15.3 | 61.4 ± 16.0 |
| Age groups at NTMD | ||||
| 18–34 years | 234 (18.5) | 1777 (16.9) | 26 (5.39) | 299 (7.21) |
| 35–54 years | 340 (26.9) | 2924 (27.7) | 80 (16.6) | 811 (19.6) |
| 55–74 years | 482 (38.2) | 3906 (37.1) | 267 (55.4) | 2027 (48.9) |
| 75 years and over | 206 (16.3) | 1936 (18.4) | 109 (22.6) | 1008 (24.3) |
| Smoking status | ||||
| Never smoker/not recorded | 592 (46.9) | 5044 (47.8) | 141 (29.3) | 1461 (35.3) |
| Current smoker | 332 (26.3) | 2439 (23.1) | 150 (31.1) | 1176 (28.4) |
| Former smoker | 338 (26.9) | 3060 (29.0) | 191 (39.6) | 1508 (36.4) |
| Body mass index (kg/m2) | (n = 1156) | (n = 9725) | (n = 466) | (n = 4027) |
| Underweight (< 18.5) | 126 (10.9) | 468 (4.81) | 65 (14.0) | 243 (6.03) |
| Healthy weight (18.5–24.9) | 549 (47.5) | 3925 (40.4) | 243 (52.2) | 1597 (39.7) |
| Overweight (25.0–29.9) | 322 (27.9) | 3171 (32.6) | 109 (23.4) | 1287 (32.0) |
| Obese (> = 30) | 159 (13.8) | 2161 (22.2) | 49 (10.5) | 900 (22.4) |
| CRD comorbidities | n = 482 (38.2) | n = 4145 (39.3) | ||
| Asthma | 201 (15.9) | 2250 (21.3) | 201 (41.7) | 2250 (54.3) |
| Bronchiectasis | 157 (12.4) | 1074 (10.2) | 157 (35.6) | 1074 (25.9) |
| Cystic fibrosis | 10 (0.79) | 35 (0.33) | 10 (2.07) | 35 (0.84) |
| COPD | 309 (24.5) | 2215 (21.0) | 309 (64.1) | 2215 (53.4) |
| Interstitial lung disease | 30 (2.38) | 220 (2.09) | 30 (6.22) | 220 (5.31) |
Continuous data is reported as mean ± standard deviation. Categorical data is presented as count (percent). Percentages may not sum to 100 due to rounding. NTMD, nontuberculous mycobacterial disease; COPD, chronic obstructive pulmonary disease; CRD, chronic respiratory disease (asthma, bronchiectasis, cystic fibrosis, COPD, interstitial lung disease)