Table 1.
Diagnostic certainty, n (%) | n = 2467 |
Possible | 1717 (69.6) |
Probable | 699 (28.3) |
Proven | 51 (2.1) |
Type of IFI, n (%) | n = 2467 |
Aspergillus-infected patients | 81 (3.3) |
Candida-infected patients | 294 (11.9) |
Not identifiable | 2092 (84.8) |
Diseases, n (%) | n = 2467 |
Gastrointestinal mycosisa | 23 (0.9) |
Fungemia | 56 (2.3) |
Respiratory mycosisb | 1063 (43.1) |
Not identifiable | 1325 (53.7) |
Duration of treatment, n (%) (weeks) | n = 2467 |
≥ 4 | 102 (4.1) |
≥ 2 to < 4 | 518 (21.0) |
≥ 1 to < 2 | 874 (35.4) |
< 1 | 973 (39.4) |
Fever, n (%) | (n = 2458)c |
Yes | 1403 (57.1)d |
No | 986 (40.1) |
Not examined | 69 (2.8) |
Imaging examinations, n (%)e | |
Chest radiography | n = 2467 |
Normal | 23 (0.93)f |
Abnormal | 438 (17.8)f |
Not examined | 2006 (81.3) |
Chest CT | (n = 2462)g |
Normal | 20 (0.8)h |
Abnormal | 914 (37.1)h |
Not examined | 1528 (62.1) |
Other imaging examination | (n = 2465)i |
Normal | 15 (0.6)j |
Abnormal | 92 (3.7)j |
Not examined | 2358 (95.7) |
Mycological examinations, n (%) | n = 2467 |
Positive | 422 (17.1) |
Negative | 770 (31.2) |
Not examined | 1275 (51.7) |
CT computed tomography, FAS full analysis set, IFI invasive fungal infection, SD standard deviation
aGastrointestinal mycoses were suspected or confirmed gastroenteritis (diarrhea and abdominal pain, or incidence confirmed by fecal culture, respectively)
bRespiratory mycoses included suspected or clinically confirmed pneumonia due to Candida or Aspergillus spp.
cData unavailable from nine patients; gfive patients; and iseven patients for fever, chest CT, and other imaging examinations, respectively
dBody temperature (mean [± SD]) of patients with fever was 38.6 °C (± 0.7); data were collected from 1400 patients (missing data, n = 3)
ePatients may have received more than one type of imaging examination
fThe longest diameter of the lesion was measurable for n = 6 (0.2% of 438 patients); hn = 42 (1.7% of 914 patients); and jn = 5 (0.2% of 92 patients) for chest radiography, chest CT, and other imaging examinations, respectively