Table 2.
Mean medications over time: all eyes and low and high IOP subgroups
| All eyes (n = 52) | Baseline IOP ≤ 16.5 mmHg (n = 26) | Baseline IOP > 16.5 mmHg (n = 26) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Mean medication (n) ± SE* | Mean difference (n) | Medication change (%) | Mean medication (n) ± SE | Mean difference (n) | Medication change (%) | Mean medication (n) ± SE | Mean difference (n) | Medication change (%) | |
| Baseline | 1.6 (0.2) | – | – | 1.7 (0.2) | – | – | 1.5 (0.3) | – | |
| Day 1 | 0.5 (0.1) | − 1.1 | − 68.8 | 0.7 (0.2) | − 1.0 | − 58.8 | 0.4 (0.2) | − 1.1 | − 73.3 |
| Week 1 | 0.6 (0.2) | − 1.0 | − 62.5 | 0.7 (0.2) | − 1.0 | − 58.8 | 0.6 (0.2) | − 0.9 | − 60.0 |
| Month 1 | 0.7 (0.1) | − 0.9 | − 56.3 | 0.8 (0.2) | − 0.9 | − 52.9 | 0.6 (0.2) | − 0.9 | − 60.0 |
| Month 3 | 1.0 (0.2) | − 0.6 | − 37.5 | 0.8 (0.2) | − 0.9 | − 52.9 | 1.1 (0.3) | − 0.4 | − 26.7 |
| Month 6 | 0.8 (0.1) | − 0.8 | − 50.0 | 0.7 (0.2) | − 1.0 | − 58.8 | 1.0 (0.2) | − 0.5 | − 33.3 |
| Month 12 | 0.8 (0.1) | − 0.8 | − 50.0 | 0.6 (0.2) | − 1.1 | − 64.7 | 1.0 (0.2) | − 0.5 | − 33.3 |
*Reported are least squares means and associated standard errors from a mixed model for repeated measure analysis. Per Bonferroni pairwise comparison, the difference from baseline in mean medications is statistically significant at each follow-up visit (P < 0.05) except at month 3 (P = 0.154)