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. 2017 Dec 1;25(4):1204–1236. doi: 10.1007/s12350-017-1131-5

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Representative case of ¹²³I-MIBG scintigraphy and ¹¹C-hydroxyephedrine PET A male in his 40s suffered from dilated cardiomyopathy, with a left ventricular ejection fraction of approximately 30%. An early anterior planar image at 15 min after injection (A) and a late anterior planar image starting at 4 hours after injection (B) are acquired to calculate the heart-to-mediastinum ratio (HMR) and the washout ratio. Calculated early HMR, delayed HMR, and washout ratio were 1.7, 1.4, and 40.3%, respectively. Whole retention index from ¹¹C-hydroxyephedrine PET was calculated as 0.044. Distribution of sympathetic nerve system was lower especially in the lateral wall