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. 2017 Dec 1;25(4):1204–1236. doi: 10.1007/s12350-017-1131-5

Table 3.

Tracers for metabolic imaging

Tracer Chemical structure Characteristics Approval year
FDA Europe Japan
 SPECT
 123I-BMIPP graphic file with name 12350_2017_1131_Figd_HTML.gif Long-chain fatty acid analogue – – 1993
 123I p-IPPA graphic file with name 12350_2017_1131_Fige_HTML.gif Long-chain fatty acid analogue – – –
 123I o-IPPA graphic file with name 12350_2017_1131_Figf_HTML.gif Long-chain fatty acid analogue – – –
 123I-9-MPA graphic file with name 12350_2017_1131_Figg_HTML.gif Long-chain fatty acid analogue – – –
PET
 18F-FDG graphic file with name 12350_2017_1131_Figh_HTML.gif Glucose analog 1997 1994* 2002
 18F-FTHA graphic file with name 12350_2017_1131_Figi_HTML.gif Long-chain fatty acid analog – – –
 11C-palmitatic acid graphic file with name 12350_2017_1131_Figj_HTML.gif Long-chain fatty acid analog – – –
 11C-acetic acid graphic file with name 12350_2017_1131_Figk_HTML.gif 11C labeled acetic acid, oxidative metabolism – – –

BMIPP, beta-methyl-p-iodophenylpentadecanoic acid; IPPA, iodophenylpentadecanoic acid; 9-MPA, iodophenyl-9-methyl-pentadecanoic acid; FDG, fluorodeoxyglucose; FTHA, fluoro-6-thia-heptadecanoic acid

*EURD List Juli 2017: http://www.ema.europa.eu/docs/en_GB/document_library/Other/2012/10/WC500133159.xls