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. 2017 Dec 1;25(4):1204–1236. doi: 10.1007/s12350-017-1131-5

Table 4.

Tracers for sympathetic imaging

Tracer Chemical structure Approval year
FDA Europe Japan
Sympathetic nervous system
 Presynaptic
  Catecholamine derivative 123I-MIBG graphic file with name 12350_2017_1131_Figl_HTML.gif 2008 1995** 1992
11C-hydroxyephedrine graphic file with name 12350_2017_1131_Figm_HTML.gif – – –
18F-LMI1195 graphic file with name 12350_2017_1131_Fign_HTML.gif – – –
18F-4-fluorometaraminol
(4-[18F]fluorometaraminol)		 graphic file with name 12350_2017_1131_Figo_HTML.gif – – –
  Catecholamine 18F-fluorodopamine graphic file with name 12350_2017_1131_Figp_HTML.gif – – –
11C-epinephrine graphic file with name 12350_2017_1131_Figq_HTML.gif – – –
11C-phenylephrine graphic file with name 12350_2017_1131_Figr_HTML.gif – – –
Postsynaptic
 α-receptor 11C-prazosin graphic file with name 12350_2017_1131_Figs_HTML.gif – – –
 β-receptor 11C-CGP12177 graphic file with name 12350_2017_1131_Figt_HTML.gif – – –
11C-CGP12388 graphic file with name 12350_2017_1131_Figu_HTML.gif – – –
18F-fluorocarazolol graphic file with name 12350_2017_1131_Figv_HTML.gif – – –
Parasympathetic nervous system
 Presynaptic Vesicular acetylcholine transporter 18F-fluoroethoxybenzovesamicol graphic file with name 12350_2017_1131_Figw_HTML.gif – – –
 Postsynaptic Muscarine 11C-methyl QNB graphic file with name 12350_2017_1131_Figx_HTML.gif – – –
11C-methyl TRB graphic file with name 12350_2017_1131_Figy_HTML.gif – – –

**EURD list nov 2012 http://www.ema.europa.eu/docs/en_GB/document_library/Other/2012/04/WC500124999.xls