Table 1. Senescence-Associated Secretory Phenotype of TDF-FTC Treated HUVECs.
Cytokines were measured by an antibody array and values are expressed as relative to control.
| Name | TDF-FTC | Name cont. | TDF-FTC cont. |
|---|---|---|---|
| Angiogenin | 3.292861 | LIF | 4.444799 |
| BDNF | 4.835223 | Light | 3.200824 |
| BLC | 3.950735 | MCP-1 | 4.404267 |
| EGF | 4.497927 | MCP-2 | 2.155095 |
| Eotaxin-1 | 5.544542 | MCP-4 | 3.813051 |
| Eotaxin-2 | 4.617339 | M-CSF | 2.910713 |
| Eotaxin-3 | 5.286011 | MDC | 5.277246 |
| FGF-4 | 0 | MIF | 3.472801 |
| FGF-6 | 5.404993 | MIG | 2.880962 |
| FGF-7 | 2.690579 | MIP-1 beta | 3.171541 |
| FGF-9 | 2.679582 | MIP-1 delta | 34.92573 |
| Flt-3 Ligand | 42.58763 | MIP-3 alpha | 5.964816 |
| Fractalkine | 3.120375 | NAP-2 | 4.621764 |
| GCP-2 | 6.316612 | NT-3 | 4.194772 |
| GDNF | 4.015717 | NT-4 | 6.497669 |
| GM-CSF | 4.297755 | Oncostatin M | 4.81561 |
| GRO | 6.478263 | Osteopontin | 5.388738 |
| GRO alpha | 5.457758 | Osteoprotegerin | 1.854735 |
| HGF | 2.866196 | PARC | 1.906955 |
| I-309 | 0.712365 | PDGF-BB | 3.002625 |
| IFN-gamma | 4.114323 | PLGF | 1.764793 |
| IGF-1 | 4.84196 | RANTES | 2.992735 |
| IGFBP-1 | 4.430662 | SCF | 5.807743 |
| IGFBP-2 | 3.658811 | SDF-1 | 2.176554 |
| IGFBP-3 | 2.949313 | TARC | 4.312071 |
| IGFBP-4 | 9.790448 | TGF beta 1 | 1.618843 |
| IL-1 alpha | 1.573047 | TGF beta 2 | 2.943513 |
| IL-1 beta | 3.838401 | TGF beta 3 | 5.057033 |
| IL-12p40/p70 | 12.4681 | Thrombopoietin | 3.717685 |
| IL-15 | 4.047189 | TIMP-1 | 3.52869 |
| IL-16 | 5.903197 | TIMP-2 | 2.980767 |
| IL-2 | 2.062056 | TNF alpha | 4.969746 |
| IL-3 | 3.463601 | TNF beta | 6.2782 |
| IL-4 | 3.243654 | VEGF-A | 2.689809 |
| IL-5 | 2.076315 | CCL23 | 7.640963 |
| IL-6 | 5.151946 | ENA-78 | 2.619985 |
| IL-7 | 4.194004 | ||
| IL-8 | 4.305946 | ||
| IP-10 | 7.109539 | ||
| Leptin | 1.683492 |