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. 2018 Aug 2;17(14):1772–1783. doi: 10.1080/15384101.2018.1496745

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Figure 1. — RHPN1-AS1 is preferentially downregulated in NSCLCs with gefitinib resistance. (A) Relative expression of RHPN1-AS1 in gefitinib sensitive group (n = 44) and gefitinib resistance group (n = 40) in NSCLC patients; (B) Relative expression of RHPN1-AS1 in a panel of NSCLC cell lines; (C) Determination of gefitinib IC₅₀ via CCK8 assay in a panel of NSCLC cell lines; (D) The correlation between of the amount of pcDNA-RHPN1-AS1 and gefitinib IC₅₀ in PC9GR cells; (E) The overall survival (OS) between RHPN1-AS1 low group (n = 46) and RHPN1-AS1 high group (n = 38) in NSCLC patients. Data are presented as the mean ± SD. (**P < 0.01, ***P < 0.001).