Table 2.
Unique proteins from bortezomib/doxorubicin-treated RPMI8226 cells interacting with PSMA3.
| UniProt ID | Protein name | Gene Name | Molecular mass (Da)/pI | Number of peptides (95%) | |
|---|---|---|---|---|---|
| 1 | P68371 | Tubulin beta-4B chain | TUBB4B | 49,831/4.79 | 7 |
| 2 | P35579 | Myosin heavy chain 9 | MYH9 | 226,532/5.5 | 6 |
| 3 | P33241 | 47 kDa actin binding protein | LSP1 | 37,192/4.69 | 2 |
| 4 | P69905 | Hemoglobin subunit alpha | HBA1 | 15,258/8.72 | 1 |
| 5 | Q99880 | Histone H2B type 1-L | HIST1H2BL | 13,950/10.31 | 1 |
| 6 | P09651 | Heterogeneous nuclear ribonucleoprotein A1 | HNRNPA1 | 38,747/9.17 | 8 |
| 7 | Q15717 | ELAV-like protein 1 | ELAVL1 | 36,092/9.23 | 1 |
| 8 | Q2TAM9 | Tumor suppressor candidate gene 1 protein | TUSC1 | 23,390/11.18 | 1 |
| 9 | P31942 | Heterogeneous nuclear ribonucleoprotein H3 | HNRNPH3 | 36,926/6.37 | 1 |
| 10 | P55795 | Heterogeneous nuclear ribonucleoprotein H2 | HNRNPH2 | 49,264/5.79 | 1 |
| 11 | Q2M243 | Coiled-coil domain-containing protein 27 | CCDC27 | 75,354/5.53 | 1 |
The intensity of cells’ color reflects the possibility of the protein to be a potential substrate for ubiquitin-independent proteolysis due to harboring long-stretched disordered region (more than 30 amino acids in length).