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. 2018 Jul 31;17(14):1797–1811. doi: 10.1080/15384101.2018.1496748

Figure 2.

Figure 2.

SkQ1 suppressed proliferation and increased population of multinucleated cells in HT1080 and RD. A. SkQ1 (20 nM, 40 nM) inhibited proliferation of HT1080 cells compared to control and C12TPP (40 nM); statistical analysis of phase contrast microscopy. B. SkQ1 (20 nM, 40 nM) inhibited proliferation of RD cells compared to control and C12TPP (40 nM); statistical analysis of phase contrast microscopy. C. Multinucleated HT1080 cells after incubation with SkQ1 (20 nM, 48 hours); green – β-actin, blue – DNA; immunofluorescence microscopy, scale bar 10μm. D. SkQ1 (20 nM, 40 nM, 48 hours) increased population of multinucleated cells in HT1080; statistical analysis of immunofluorescence microscopy. Student t-test, (**) for p < 0.01, (***) for p < 0.001. E. An enhancement of multinucleated cells’ population in RD after SkQ1 (20 nM, 40 nM, 72 hours) treatment; statistical analysis of immunofluorescence microscopy. Student t-test, (**) for p < 0.01, (***) for p < 0.001.