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. 2018 Jul 31;17(14):1797–1811. doi: 10.1080/15384101.2018.1496748

Figure 4.

Figure 4.

SkQ1 induced changes in number and characteristics of mitosis in HT1080 cells. A. Reduction of mitotic cell population by SkQ1 (40 nM C12ТРР, 40 nM SkQ1, 24 and 96 hours). B. SkQ1 (40 nM, 42 and 90 hours) diminished mitotic cell population in partially synchronized by serum deprivation cell culture. C. SkQ1 (40 nM, 72 hours) induced changes in phase duration of morphologically normal mitoses (P – prophase, М – metaphase, А – anaphase, Т – telophase). D. SkQ1 (40 nM, 72 hours) induced changes in phase duration of prolonged mitoses. E. SkQ1 (20 nM, 72 hours) caused prolonged mitoses in mitotic cell population. F. SkQ1 (40 nM, 24 hours) induced changes in distribution of dividing cells over mitotic phases (nТ – normal telophase, aT – asymmetrical in shape telophase).