Skip to main content
. 2018 Sep 11;13(9):e0203890. doi: 10.1371/journal.pone.0203890

Table 3. Adjusted risk factors for polypharmacy in participants.

Adjusted Prevalence Ratios (95% CI)
Overall HIV Positive HIV Negative
HIV status
Positive 1.36 (1.26 to 1.46) a - -
Negative Referent - -
Age
≥ 50 y 1.61 (1.47 to 1.76) a 1.22 (1.13 to 1.33) a 1.56 (1.32 to 1.84) a
< 50 y Referent Referent Referent
Race/ethnicity
Non-Hispanic black 0.73 (0.65 to 0.82) a 0.83 (0.74 to 0.92) a 0.94 (0.77 to 1.16)
Other 0.86 (0.75 to 0.99) a 1.04 (0.93 to 1.16) 0.82 (0.63 to 1.08)
Non-Hispanic white Referent Referent Referent
Medication insurance coverage
Yes 1.32 (1.16 to 1.49) a 1.14 (1.01 to 1.27) a 1.90 (1.59 to 2.28) a
No Referent Referent Referent
Enrollment period
Early recruitment (1987–1991) 1.26 (1.14 to 1.40) a 1.08 (0.99 to 1.18) a 1.42 (1.18 to 1.72) a
Late recruitment (2001–2003) Referent Referent Referent
Viral Load - -
Detectable - 0.97 (0.92 to 1.02) -
Undetectable - Referent -
CD4+ count (cells/mm3)
< 500 - 0.97 (0.91 to 1.02) -
≥ 500 - Referent -
ART adherence
95%-99% - 1.04 (0.99 to 1.10) -
75%-94% - 0.98 (0.89 to 1.09) -
<75% - 0.95 (0.80 to 1.14) -
100% - Referent -
ART medication use - 1.15 (1.12 to 1.18) a -

Abbreviation: ART, antiretroviral therapy; a Statistically significant; p values were calculated using generalized estimating equation models.