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KM estimates of BPAR by dose groups. BPAR was defined as acute/active cellular rejection as interpreted by the central blinded pathologist, according to the Banff 97 working classification.21 Data are based on all biopsies (including for-cause and protocol biopsies). Data in graphs show the first occurrence of BPAR. Data presented are from the full analysis set for the parent study (A3921030; NCT00483756), months 0 to 12, and the LTE study (A3921050; NCT00658359), months 12 to 72.
