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. 2018 Sep 11;7:e37125. doi: 10.7554/eLife.37125

Table 1. Significant positive clusters of noxious-evoked brain activity, observed across the whole group (n = 13, cluster forming threshold: z = 3.1, cluster significance threshold, p = 0.05).

This table provides an anatomical description and the location of the peak z-statistic within each active brain region. The group activity reported consisted of 14 distinct clusters, some of which spanned multiple brain regions.

Anatomical description of location of activity Maximum z-statistic within cluster Coordinates of maximum z-statistic in infant template space
X Y Z
Post-central gyrus Contra 4.8 7.7 −27.5 50.7
Ipsi 4.7 −23.2 −27.5 43.8
Posterior cingulate sulcus Contra 4.8 6.9 −23.2 36.0
Ipsi 3.8 −6.0 −20.6 34.3
Superior parietal lobule Contra 4.8 12.9 −44.6 47.2
Ipsi 4.7 −14.6 −43.8 43.8
Thalamus Contra 4.7 16.3 −19.7 12.0
Ipsi 4.6 −13.8 −24.0 16.3
Supra-marginal gyrus Ipsi 4.7 −25.8 −29.2 37.8
Contra 4.6 30.1 −24.9 28.3
Superior frontal sulcus Contra 4.7 16.3 −4.3 44.6
Middle frontal gyrus Ipsi 4.7 −27.5 0.9 30.0
Contra 4.0 24.1 5.2 33.5
Cuneus Contra 4.7 7.7 −53.2 26.6
Ipsi 4.2 −5.1 −50.7 23.2
Superior parietal lobe / Precuneus Contra 4.7 5.2 −35.2 39.5
Ipsi 4.0 −0.9 −43.8 41.2
Pre-central gyrus / Central sulcus Contra 4.6 24.1 −14.6 45.5
Ipsi 3.9 −8.6 −23.2 53.2
Posterior insula Contra 4.6 19.0 −19.7 24.0
Parietal operculum Ipsi 4.6 −34.4 −21.4 18.0
Superior temporal gyrus / Posterior operculum Contra 4.6 31.0 −27.5 22.3
Occipital gyrus Ipsi 4.6 −12.0 −63.5 21.4
Anterior cingulate cortex Ipsi 4.2 −1.7 14.7 24.0
Contra 3.9 4.3 12.1 25.7
Superior temporal gyrus Ipsi 4.2 −27.5 −28.3 12.8