Table 1. Candidate reentrant domains identified among predicted bitopic proteins from E. coli.
Sequences were selected from the Membranome database of 196 known and predicted bitopic folds from E. coli, based on the criteria described in the text. Sequences highlighted in red represent the predicted transmembrane domain (TMHMM Server v2.0, http://www.cbs.dtu.dk/services/TMHMM/).
| Name | Function | Sequence of N-terminus (residues 1–50) | |
|---|---|---|---|
| HofN | Putative DNAutilization protein | MNPPINFLPWRQQRRTAFLRFWLLMFVAPLLLAVGITLILRLTGSAEARI | |
| LpxL | Lipid A biosynthesis lauroyltransferase |
MTNLPKFSTALLHPRYWLTWLGIGVLWLVVQLPYPVIYRLGCGLGKLALR | |
| LpxM | Lipid A biosynthesis myristoyltransferase |
METKKNNSEYIPEFDKSFRHPRYWGAWLGVAAMAGIALTPPKFRDPILAR | |
| LpxP | Lipid A biosynthesis palmitoleoyltransferase |
MFPQCKFSREFLHPRYWLTWFGLGVLWLWVQLPYPVLCFLGTRIGAMARP | |
| YihG | Probably acyltransferase | MANLLNKFIMTRILAAITLLLSIVLTILVTIFCSVPIIIAGIVKLLLPVP | |