Skip to main content
. 2018 Aug 28;91(9):e867–e877. doi: 10.1212/WNL.0000000000006082

Figure 2. CSF biomarkers of neuroinflammation and cerebrovascular changes, CSF tau, and cortical atrophy.

Figure 2

(A, B) Association between CSF YKL-40 and total tau (t-tau) and CSF YKL-40 and phosphorylated tau (p-tau), respectively, in study participants with normal (β-amyloid [Aβ]−) and pathologic (Aβ+) CSF status. Unstandardized B coefficients and p values for slopes are from linear regression models. The results were very similar when adjusting for the covariates (age, sex, APOE ε4 genotype, and anti-inflammatory medications). (C) Associations between YKL-40 and cortical thickness. Voxel-wise regression analysis corrected for age, sex, and APOE ε4.