Table 2.

Immunohistochemical and Molecular Profile of Uterine PEComas

Case #	HMB-45	Melan-A	MiTF	Cathepsin K	Desmin	h-caldesmon	SMA	TFE3	RAD51B
1	4+ H	3+ S	2+ H	4+ S	0	1+	0	-	-
2	PPR	PPR	NP	NP	0	NP	PPR	NP	NP
3	3+ S	1+ S	1+ W	4+ S	1+ S	2+ H	2+ S	-	-
4	4+ S	4+ H	2+ W	4+ S	1+ W	3+ H	PPR	-	-
5	3+ H	PPR	NP	NP	NP	NP	4+ S	-	-
6	4+ S	1+ W	0	4+ S	0	1+ S	2+ S	-	-
7	3+ S	0	0	4+ S	4+ S	4+ S	3+ S	Failed	Failed
8	4+ S	3+ H	1+ W	4+ S	1+ S	1+ W	1+ H	-	-
9	4+ S	4+ S	0	4+ S	1+ H	2+ S	4+ S	-	-
10	3+ S	1+ W	1+ W	4+ S	3+ H	1+ S	1+ S	-	-
11	4+ S (Ep) 0 (Sp)	4+ S (Ep) 0 (Sp)	0 (Ep/Sp)	4+ S (Ep) 0 (Sp)	0 (Ep) 4+ (Sp)	0 (Ep) 4+ (Sp)	0 (Ep) 4+ (Sp)	-	-
12	2+ S	1+ S	2+ W	4+ S	2+ S	0	0	-	RAD51B-OPHN1
13	4+ S	2+ H	1+ W	4+ H	1+ S	0	NP	-	-
14	4+ S	0	0	4+ S	0	0	4+ S	PSF-TFE3	-
15	4+ S	3+ H	4+ S	4+ S	3+ S	0	2+ H	-	-
16	4+ S	0	1+ W	4+ S	4+ S	0	4+ S	-	-
17	4+ S	0	1+ W	4+ S	2+ S	0	PPR	-	-
18	4+ S	1+ H	3+ H	4+ S	4+ S	4+ S	4+ S	-	-
19	4+ S	4+ H	4+ W	4+ S	3+ S	2+ S	4+ H	-	-
20	1+ H	1+ S	3+ W	4+ S	2+ S	4+ S	4+ S	-	-
21	4+ S	4+ S	4+ S	2+ W	0	0	0	-	-
22	2+ S	2+ S	0	2+ H	4+ S	4+ S	3+ S	-	-
23	4+ S	1+ S	3+ W	4+ S	4+ S	4+ S	4+ S	-	-
24	2+ S	1+ H	4+ S	3+ S	4+ S	4+ S	4+ S	-	-
25	4+ H	0	4+ H	4+ S	4+ S	4+ S	4+ S	-	-
26	4+ S	0	3+ H	4+ S	4+ S	4+ S	4+ S	-	-
27	4+ S	0	0	4+ S	4+ S	4+ S	4+ S	-	-
28	4+ S	1+ W	2+ W	4+ H	0	4+ S	4+ S	-	-
29	4+ H	1+ W	3+ H	4+ S	4+ S	2+ S	4+ S	-	-
30	4+ S	0	4+ S	4+ S	4+ S	2+ S	4+ S	-	-
31	4+ S	4+ S	2+ H	4+ S	0	1+ H	2+ S	-	-
32	1+ S	1+ S	0	4+ S	4+ S	4+ S	4+ S	-	-

<1% (0), 1–5% (1+), 6–25% (2+), 26–50% (3+), >50% (4+), strong (S), heterogeneous (H), weak (W)

SMA=smooth muscle actin; PPR=positive per report; NP=not performed; Ep=epithelioid component; Sp=spindled component