Table 2.

Summary of pathologic and major laboratory findings of EBV+ MZL cases

Patient	Anatomic Site	H&E	CD20	CD79a	CD138 or CD38	MUM-1	κ/λ	IgG/IgM/IgA	EBER/LMP1	Ki-67	MyD88	Ig PCR Clonality
1	Left inguinal LN	Nodular infiltrate of monocytoid cells.	Pos	Pos	Both focally pos	Pos	Kappa	IgG	Pos/Neg	Low	WT	IgH pos
2	Subcutaneous masses, arm, abdomen	Lymphocytic/plasmacellular, Biphasic pattern	Pos	Pos	CD38 pos, CD138 neg	Pos	Kappa	IgG	Pos/Neg	Low	WT	Poor DNA
3	Skin, flank, abdomen	Lymphocytic/plasmacellular, Polymorphic	Partially pos	Pos	CD138 pos	Pos	Lambda	IgG	Pos/Neg	Moderate	WT	IgH and IgK pos
4	Skin, arm	Lymphocytic/plasmacellular, Biphasic pattern	Partially pos	Pos	CD138 partially pos	Pos	Lambda	IgG	Pos/Neg	Moderate	N.D.	IgH and IgK pos
5	Periparotid soft tissue	Lymphocytic/plasmacellular, Biphasic pattern	Partially pos	Pos	CD138 variably pos	Pos	Kappa	All neg	Pos/Neg	Low	WT	IgH pos
6	Lung	Lymphocytic/plasmacellular, Biphasic pattern	Partially pos	Pos	CD138 pos	Pos	Lambda	IgG	Pos/Pos	Moderate	N.D.	IgH and IgK pos
	Lymph node (2nd Bx)	Classical Hodgkin lymphoma, EBV-positive, LD										IgH and IgK Pos (unrelated)
7	Breast	Monocytoid/plasmacellular, BiphasicMott cells and Russell bodies	Partially pos	N.D.	Pos	N.D.	Kappa	IgG	Pos/N.D.	Low	N.D.	N.D.
8	Skin, arm	Lymphocytic/plasmacellular, Polymorphic	Partially pos	Pos	N.D.	Pos	Lambda	N.D.	Pos/N.D.	Moderate	N.D.	N.D.
9	Parotid gland	Monocytoid/plasmacellular, Biphasic	Pos	N.D.	CD138 partially pos	Pos	Kappa	IgM	Pos/Neg	Moderate	WT	IgH and IgK pos
10	Parotid gland	Monocytoid/plasmacellular, Biphasic	Pos	N.D.	CD138 partially pos	Pos	Kappa	IgM	Pos/Pos	Low	WT	IgH and IgK pos

Abbreviations: LN, lymph node; Pos, positive; N.D., not done; WT, wild type; LD, lymphocyte depleted.