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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Hear Res. 2018 Mar 11;368:28–40. doi: 10.1016/j.heares.2018.03.002

Figure 7.

Figure 7

Time courses of dexamethasone-phosphate and dexamethasone base concentrations derived from simulations fitted to the measured sample data. Concentrations are shown for perilymph of the entire scala tympani pooled. Perilymph concentration is initially higher with application of dexamethasone-phosphate, due to the higher applied concentration, and was higher at the time of sampling which commenced after 1 hour as indicated. Nevertheless, the higher dosing is short-lived and after 2.3 hours concentration falls below that when dexamethasone suspension is administered.