Table 3. Crude and adjusted OR for the association of ACE ID and TNF -308G/A polymorphisms with ROP risk.

Polymorphism	OR (95%CI)	P	aOR (95%CI)a	P
ACE ID
II genotype	1.000
ID genotype	0.793 (0.627-1.003)	0.053	0.603 (0.427-0.893)	0.034
DD genotype	0.700 (0.532-0.921)	0.011	0.468 (0.229-0.626)	0.002
I allele	1.000
D allele	0.829 (0.721-0.953)	0.009	0.698 (0.294-0.883)	<0.001
TNF -308G/A
GG genotype	1.000
GA genotype	1.656 (1.275-2.149)	<0.001	1.956 (1.396-2.465)	<0.001
AA genotype	2.516 (1.059-5.975)	0.037	2.809 (1.802-4.484)	<0.001
G allele	1.000
A allele	1.670 (1.324-2.106)	<0.001	1.776 (1.446-2.561)	<0.001

^aAdjusted for gestational age at birth, birth weight and gender of the subjects.