Fig. 4. FOXJ2 overexpression inhibited the migration and invasive ability of HCC cells.

a HepG2 and MHCC-97H cells were transduced with FOXJ2 overexpressing (FOXJ2 OE) or control (vector) lentivirus. Cells without any treatment (WT) served as negative control. Ectopic expression of FOXJ2 was evaluated using western blotting at 48 h after viral transduction. Representative blots from three independent experiments are shown. b, c Transwell assays were conducted to determine the migration (b) and invasion (c) ability of HepG2 and MHCC-97H cells. Scale bar: 100 μm. **P < 0.01, ***P < 0.001 versus WT and vector