Table 1.
Genetic and the antigenic relationships between the A/Anhui/1/2013(AH/1) virus and two H7N9 highly pathogenic influenza viruses
| Virus | Gene identity (%) | Cross-reactive HI antibody titers of ferret antisera induced by different viruses | ||||
|---|---|---|---|---|---|---|
| Hemagglutinin | Neuraminidase | |||||
| Nucleotide | Amino acid | Nucleotide | Amino acid | AH/1a | H7N9/AAcab | |
| A/Anhui/1/2013 (H7N9)(AH/1) | 100 | 100 | 100 | 100 | 640 | 160 |
| H7N9/AAca | 100 | 100 | 100 | 100 | 320 | 160 |
| A/chicken/Hunan/S1220/2017(H7N9)(CK/SD1220) | 97.9 | 97.1 | 97.9 | 97.2 | 80 | 20 |
| CK/SD008-PB2/627K | 98.5 | 97.9 | 98.6 | 98.3 | 320 | 80 |
aThe sera were collected in the previously study by Zhang et al.2. Ferrets were inoculated intranasally with 106EID50 of the AH/1 virus and were euthanized for serum collection three weeks post-inoculation
bThe sera were collected in the previously study by Kong et al.21. Ferrets were inoculated intranasally with one dose of 106EID50 of the live attenuated vaccine H7N9/AAca, and serum samples were collected from the ferrets three weeks post-inoculation