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. 2018 Sep 5;9:1183. doi: 10.3389/fphys.2018.01183

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Copyright © 2018 dos Santos, Righetti, Camargo, Saraiva-Romanholo, Aristoteles, de Souza, Fukuzaki, Alonso-Vale, Cruz, Prado, Leick, Martins and Tibério.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of ROCK inhibitor and anti-IL17 in cells involved in hyper-responsiveness. (A) ROCK1 in the airway, (B) ROCK1 in the alveolar septa, (C) ROCK2 in the airway, and (D) ROCK2 in the alveolar septa, levels expressed as numbers of positive cells/10⁴ μm². ^∗p < 0.05 compared to the SAL group; ^∗∗p < 0.05 compared to the OVA group; ^#p < 0.05 compared to OVA-RHOi and OVA-anti-IL17 groups; & p < 0.05 compared to the OVA-anti-IL17 group.