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. 2018 Sep 5;9:1183. doi: 10.3389/fphys.2018.01183

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Copyright © 2018 dos Santos, Righetti, Camargo, Saraiva-Romanholo, Aristoteles, de Souza, Fukuzaki, Alonso-Vale, Cruz, Prado, Leick, Martins and Tibério.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of anti-IL17 and the ROCK inhibitor on IL-17 gene expression and IL-17 positive cell number. (A) Number of IL-17 positive cells in the airways, (B) number of IL-17 positive cells in the alveolar septa, and (C) the levels of IL-17 mRNA assessed by RT-PCR (AU). ^∗p < 0.05 compared to the SAL group;^∗∗p < 0.05 compared to the OVA group; ^#p < 0.05 compared to OVA-RHOi group.