Table 2.
Absolute values for inflammatory markers in the alveolar septa.
| Inflammatory markers | SAL | OVA | OVA-RHOi | OVA-anti-IL17 | OVA-RHOi-anti-IL17 | |
|---|---|---|---|---|---|---|
| Alveolar septa | CD4+ (cells/104μm2) | 0.82 ± 0.24 | 10.51 ± 1.17∗ | 2.97 ± 0.47∗∗ | 2.76 ± 0.47∗∗ | 2.3 ± 0.39∗∗ |
| Alveolar septa | CD8+ (cells/104μm2) | 0.97 ± 0.35 | 14.75 ± 1.8∗ | 6.13 ± 0.77∗, ∗∗ | 5.71 ± 0.98∗, ∗∗ | 2.95 ± 0.71∗∗ |
| Alveolar septa | IL-17 (cells/104μm2) | 0.32 ± 0.05 | 4.28 ± 0.18∗ | 1.4 ± 0.14∗, ∗∗ | 1.3 ± 0.39∗, ∗∗ | 1.09 ± 0.12∗, ∗∗ |
| Alveolar septa | IL-1β (cells/104μm2) | 11.8 ± 1.37 | 20.25 ± 1.34∗ | 10.79 ± 0.85∗∗ | 14.85 ± 1.48∗∗ | 10.95 ± 1.24∗∗ |
| Alveolar septa | IL-2 (cells/104μm2) | 0.928 ± 0.085 | 3.212 ± 0.106∗ | 1.084 ± 0.410∗∗ | 1.069 ± 0.117∗∗ | 0.997 ± 0.344∗∗ |
| Alveolar septa | IL-5 (cells/104μm2) | 0.39 ± 0.07 | 5.07 ± 0.3∗ | 2.28 ± 0.3∗, ∗∗ | 1.97 ± 0.25∗, ∗∗ | 0.81 ± 0.163∗∗, $ |
| Alveolar septa | IL-6 (cells/104μm2) | 0.915 ± 0.116 | 3.979 ± 0.224∗ | 2.085 ± 0.340∗, ∗∗ | 1.33 ± 0.16∗∗ | 1.33 ± 0.44∗∗ |
| Alveolar septa | IL-10 (cells/104μm2) | 0.62 ± 0.19 | 5.86 ± 0.88∗ | 2.44 ± 0.54∗∗ | 3.48 ± 0.48∗, ∗∗ | 2.22 ± 0.36∗, ∗∗ |
| Alveolar septa | IL-13 (cells/104μm2) | 0.722 ± 0.414 | 4.690 ± 0.596∗ | 1.150 ± 0.253∗∗ | 0.324 ± 0.159∗∗ | 0.853 ± 0.199∗∗ |
| Alveolar septa | IL-4 (cells/104μm2) | 0.838 ± 0.290 | 5.227 ± 0.602∗ | 2.970 ± 0.494∗, ∗∗, # | 5.512 ± 0.947∗ | 1.482 ± 0.295∗∗, $ |
| Alveolar septa | TNF-α (cells/104μm2) | 1.182 ± 0.376 | 5.438 ± 0.543∗ | 3.401 ± 0.531∗∗∗ | 1.364 ± 0.278∗∗, & | 1.056 ± 0.246∗∗, & |
| Alveolar septa | NF-κB (cells/104μm2) | 12.992 ± 1.346 | 23.893 ± 2.616∗ | 12.15 ± 1.08∗∗ | 7.587 ± 1.089∗, ∗∗ | 11.48 ± 0.75∗∗ |
| Alveolar septa | FOXP3 (cells/104μm2) | 2.222 ± 0.285 | 7.758 ± 0.928∗ | 4.02 ± 0.7∗∗ | 4.449 ± 0.579∗, ∗∗ | 1.778 ± 0.304∗∗, $ |
| Alveolar septa | Dendritic cells (cells/104μm2) | 1.139 ± 0.301 | 8.406 ± 1.387∗ | 2.760 ± 0.432∗∗ | 1.868 ± 0.458∗∗ | 0.65 ± 0.2∗∗ |
∗p < 0.05 compared to SAL group; ∗∗p < 0.05 compared to OVA group; $p < 0.05 compared to OVA-RHOi and OVA-anti-IL17; #p < 0.05 compared to OVA-anti-IL17; &p < 0.05 compared to OVA-RHOi.